1.
Actual. SIDA
;
18(70): 135-141, nov. 2010. ilus
Article
in Spanish
| LILACS
| ID: lil-598197
ABSTRACT
En esta revisión, se resume el rol de la integrasa en la infección por VIH-1, el mecanismo de los inhibidores de la integrasa y la resistencia, con énfasis en el Raltegravir (RAL), el primer inhibidor de la integrasa autorizado para tratar la infección por VIH-1.
This review will summarize the role of integrase in HIV-1 infection, the mechanism of integrase inhibitors and resistance with an emphasis on Raltegravir (RAL), the first integrase inhibitor licensed to treat HIV-1 infection.
Subject(s)
Humans , Anti-Retroviral Agents , HIV Protease , HIV-1 , Integrase Inhibitors/pharmacology , Reverse Transcriptase Inhibitors
2.
Braz. j. infect. dis
;
14(5): 513-518, Sept.-Oct. 2010. ilus
Article
in English
| LILACS
| ID: lil-570569
ABSTRACT
This review will summarize the role of integrase in HIV-1 infection, the mechanism of integrase inhibitors and resistance with an emphasis on raltegravir (RAL), the first integrase inhibitor licensed to treat HIV-1 infection.